Inhibitors

HDAC inhibitors

Designation Cat nr Size Effect
AGK2 27228 5 mg Selective, cell-permeable inhibitor of SIRT2
CBHA 27204 5 mg Potent histone deacetylase inhibitor
EX-527 27202 1 mg Potent and selective SIRT1 class III histone deacetylase enzyme inhibitor
HC Toxin 27103 1 mg Reversible and cell-permeable inhibitor of HDACs
HNHA 27206 10 mg Cell-permeable inhibitor of HDAC activity
4-iodo-SAHA 27205 50 mg Hydrophobic derivative of SAHA, a class I and class II HDAC inhibitor, showing >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay at 1 μM
M344 27203 5 mg Human HDAC inhibitor (also known as D237 or MS 344), showing a three-fold selectivity for inhibition of HDAC6 over HDAC1
MS-275 (Entinostat) 27011 25 mg Preferential Inhibitor of HDAC1 over HDAC3, but no effect on HDAC8
Oxamflatin 27201 1 mg Potent histone deacetylase inhibitor
SAHA (Vorinostat) 27007 10 mg Potent histone deacetylase inhibitor
Scriptaid (GCK 1026) 27200 1 mg HDAC inhibitor with optimal concentration of 6-8 μM in a cell based assay and exhibiting lower toxicity than trichostatin A
s-HDAC-42 27208 1 mg Strong inhibitor of HDACs
SBHA 27210 100 mg Competitive HDAC inhibitor
Trichostatin A 27102 10 mg  
Tubastatin A 27108 10 mg Potent HDAC6 inhibitor
Valproic Acid 27207 10 g HDACs inhibitor, in particular of Class I HDACs